Press reviews


#Suicide  #VitaminD  #Depression  #Neuroprotection  #Inflammation  #Deficiency  #Supplementation  #Prevention  #MentalHealth  #SuicidalBehavior


Suicide is a major public health issue, causing nearly 700,000 deaths worldwide each year. It results from a combination of biological, psychological, and environmental factors, such as depressi...

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#Fiber  #UremicToxins  #Inflammation  #Microbiota  #Nutrition  #KidneyDisease  #Dialysis


Patients with chronic kidney disease (CKD) often suffer from an imbalance in the gut microbiota, known as dysbiosis. This disruption promotes the proliferation of bacteria that break down dietary proteins and produce uremic toxins (p-cresyl sulfate, indoxyl sulfa...

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2025-03-06

Childhood obesity: could homocysteine be the key?

Endocrinology and Metabolism

#ChildHealth  #Metabolism  #VitaminB12  #Folate  #Homocysteine  #Obesity


Childhood obesity is a rapidly growing public health concern worldwide. According to the WHO, the number of overweight or obese children and adolescents has increased tenfold in recent decades. This rise is linked to lifestyle changes, including increased consumption of ultra-process...

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2025-03-06

Pregnancy and weight: a winning balance?

Endocrinology and Metabolism

#Obesity  #Pregnancy  #FatLoss  #Nutrition  #MaternalHealth


Obesity during pregnancy is a major public health concern, as it is associated with an increased risk of complications for both the mother and the baby. Gestational diabetes raises the likelihood of having a large baby (macrosomia), making delivery more difficult. Hypertensive disorders such as gesta...

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#Cytomegalovirus  #CMV  #Hearing  #Neurodevelopment  #Prevention  #Pediatrics


Postnatal infection with cytomegalovirus (CMV) is a common viral disease that primarily affects infants, particularly in regions with a high prevalence of the virus. Generally considered benign in full-term, healthy newborns, the impact of postnatal CMV on auditory and neurologi...

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#Hearing  #Aging  #HearingLoss  #Neuroplasticity  #Dementia

Age-related hearing loss and cognitive decline are two major risk factors for dementia, a condition affecting over 55 million people worldwide. Recent studies suggest that hearing loss accelerates cognitive decline by reducing brain stimulation and promoting social isolation. Yet, despite the availability of...

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2025-03-03

Should surgery be broader?

Oncology

#IBD  #CrohnsDisease  #Surgery  #Intestine  #Inflammation    


Crohn’s disease (CD) is a chronic inflammation of the digestive tract that progresses in flare-ups. It primarily affects the terminal ileum and colon. While drug treatments (anti-inflammatory drugs, immunosuppressants, biologics) help control the disease, 60 to 70% of patients requ...

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#Leukemia  #ALL  #AML  #LongTermFollowUp  #Oncology  #Cancer    


Thanks to advances in pediatric oncology, the vast majority of children with acute leukemia are now cured. More than 90% of patients with acute lymphoblastic leukemia (ALL) and about 60 to 70% of children with acute myeloid leukemia (AML) survive thanks to progress in chemoth...

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2025-02-27

Sepsis and memory: a link not to be forgotten!

Neurology Oncology

#Leukemia  #ALL  #AML  #Infection  #Sepsis  #Neurocognition  #Memory


Children diagnosed with acute lymphoblastic leukemia (ALL) or acute myeloid leukemia (AML) are particularly vulnerable to infections due to aggressive treatments that weaken their immune systems. Chemotherapy and corticosteroids reduce natural defenses, while the use of central veno...

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2025-02-26

IVIG: an ally against fever in ALL?

Hematology Oncology

#Leukemia  #ALL  #cancer  #oncology  #pediatrics  #prophylaxis  #immunoglobulin  #fever


Acute lymphoblastic laukemia (ALL) is the most common pediatric cancer. Despite therapeutic advances, infections remain a major cause of complications and mortality. Approximately 20% of deaths related to pediatric hematologic cancer treatment are due to infe...

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#Leukemia  #Cancer  #BMI  #Obesity  #Malnutrition  #Oncology


Obesity and malnutrition in children are increasing worldwide. Recent data suggest that these factors may influence the progression of many diseases, including pediatric cancers. Among them, acute leukemia—comprising acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML)—remains the...

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2025-02-24

ALL: a constantly evolving battle

Oncology

#Leukemia  #ALL  #Oncology  #Chemotherapy  #Immunotherapy  #Innovation  

Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, accounting for 75% of childhood leukemias. It is characterized by excessive proliferation of immature cells in the bone marrow, preventing normal blood cell production and leading to fatigue, recurrent infect...

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2025-02-21

Serum: a key to better treating IBD ?

Gastroenterology and Hepatology

#IBD #CrohnsDisease #Biomarker #Gastroenterology #Metabolomics #Lipidomics

Chronic inflammatory bowel diseases (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), are digestive disorders affecting millions worldwide. These conditions are characterized by persistent inflammation of the digestive tract, occurring in flare-ups interspersed with periods of remission. While their...

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2025-02-20

Progeria: a new therapeutic avenue?

Medical Genetics

#Progeria  #PrematureAging  #CRM1  #Selinexor  #Senescence  #TargetedTherapy


Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare genetic disorder that causes premature aging. It is triggered by a mutation in the LMNA gene, leading to the abnormal production of progerin. This protein accumulates in the cell nucleus, disrupting cellular function and accelerati...

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#CysticFibrosis  #Microbiome  #InnovativeTherapies  #Probiotics  #LungInfections  #PrecisionMedicine

Cystic fibrosis is a severe genetic disease caused by mutations in the CFTR gene, disrupting ion transport and leading to thick mucus accumulation in the airways. Despite advances with CFTR modulators, these treatments remain inaccessible to some patients and...

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